Commentary
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Commentary
Practicing evidence-based medicine: The Holy Grail?
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Commentary
The art of medicine after retirement
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Commentary
Evidence or bias?
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Commentary
Interpretation of colposcopy data
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Commentary
Statistics to assess patient satisfaction with primary care called into question
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Commentary
Gingko: smart pill or not?
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Commentary
Should the Population be Offered General Health Screenings?
Photo Rounds
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Photo Rounds
A terrible itch
Applied Evidence
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Applied Evidence
Office evaluation and treatment of hemorrhoids
Clinical Inquiries
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Clinical Inquiries
What is the most effective beta-blocker for heart failure?
EVIDENCE-BASED ANSWER: Three beta-blockers—carvedilol, metoprolol, and bisoprolol—reduce mortality in chronic heart failure caused by left...
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Clinical Inquiries
Does increasing methylphenidate dose aid symptom control in ADHD?
EVIDENCE-BASED ANSWER: Most children with attention deficit/hyperactivity disorder (ADHD) who are started on methylphenidate will respond...
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Clinical Inquiries
Are tympanostomy tubes indicated for recurrent acute otitis media?
EVIDENCE-BASED ANSWER: For children with recurrent acute otitis media (here defined as 3 or more episodes in 6 months, or 4 or more in a year),...
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Clinical Inquiries
How should we manage infants at risk for group B streptococcal disease?
EVIDENCE-BASED ANSWER: Asymptomatic term infants whose mothers received adequate intrapartum antibiotic prophylaxis (defined as intravenous...
Original Research
Q&A
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Q&A
Breastfeeding reduces pain in neonates
BACKGROUND: Healthy neonates routinely undergo painful minor procedures. Evidence suggests that infants do feel pain, and painful experiences may...
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Q&A
What is the best NSAID regimen for arthritis patients with bleeding ulcer?
BACKGROUND: Patients who take NSAIDs for arthritis are at high risk for bleeding ulcers because of their age, functional disability, and the long-...
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Q&A
Zinc nasal gel effective for the common cold
BACKGROUND: Although the common cold is self-limiting, adults develop colds approximately 2 to 4 times per year. Zinc may decrease the length and...
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Q&A
Use of sputum eosinophil count decreases asthma exacerbations
BACKGROUND: Asthma exacerbations are preceded by airway hyperresponsiveness; proinflammatory cells, including eosinophils, are implicated as the...
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Q&A
Ultrasonography helpful in diagnosing developmental hip dysplasia
BACKGROUND: Developmental dysplasia of the hips is a condition that can impair normal growth and development of the hip, leading to abnormalities...
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Q&A
Low-dose tricyclics effective for depression
BACKGROUND: Despite widespread marketing of selective serotonin reuptake inhibitors (SSRIs) and other newer antidepressants, TCAs are prescribed...
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Q&A
What is a reasonable interval for retinopathy screening in patients with diabetes?
BACKGROUND: Diabetes mellitus is the leading cause of blindness among adults in the US. The onset of diabetic retinopathy is often asymptomatic,...
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Q&A
Nebulized 3% saline effective for viral bronchiolitis
BACKGROUND: Viral bronchiolitis is a common cause of illness in children aged <24 months. Studies have found no benefit in treatment with...
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Q&A
Optimal digoxin range for men is 0.5 to 0.8 ng/mL
BACKGROUND: The Digitalis Investigation Group (DIG) trial of patients with heart failure found no effect on mortality from digoxin therapy at...
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Q&A
Transdermal progesterone ineffective for menopausal symptoms
BACKGROUND: Natural progesterone is touted as treatment for the vasomotor, mood, and sexual disturbances associated with menopause. No well-...