Applied Evidence
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Applied Evidence
The Evaluation and Treatment of Tobacco Use Disorder
Clinical Inquiries
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Clinical Inquiries
What laboratory monitoring is appropriate to detect adverse drug reactions in patients on cholesterol-lowering agents?
EVIDENCE-BASED ANSWER: Recommendations for measuring serum aminotransferase levels before initiating pharmacologic treatment for...
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Clinical Inquiries
What is the best strategy for monitoring the lipid-lowering effects of medical therapy used for the primary prevention of coronary artery disease (CAD)?
EVIDENCE-BASED ANSWER: There is good evidence that treatment for primary prevention of CAD decreases risk of major first coronary events and...
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Clinical Inquiries
What are the current treatment and monitoring recommendations for hepatitis C virus (HCV)?
EVIDENCE-BASED ANSWER: Patients diagnosed with HCV should have serum liver function tests and get a baseline HCV RNA level (viral load), since...
Commentary
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Commentary
Studying Systematic Reviews
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Commentary
Why Can’t We Answer Our Questions?
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Commentary
Factors Influencing Physician Participation in Practice-Based Research Network Studies A Call for Further Research
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Commentary
The future of family medicine
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Commentary
Physicians and their fathers
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Commentary
b-Blockers for systolic dysfunction
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Commentary
An Act of Malpractice?
Original Research
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Original Research
Participation and Successful Patient Recruitment in a Randomized Clinical Trial of Dyspepsia Treatment in Primary Care
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Original Research
Rate of Case Reporting, Physician Compliance, and Practice Volume in a Practice-Based Research Network Study
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Original Research
Clinical Findings Associated with Radiographic Pneumonia in Nursing Home Residents
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Original Research
The Accuracy of Physical Diagnostic Tests for Assessing Meniscal Lesions of the Knee: A Meta-Analysis
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Original Research
Are b2-agonists Effective Treatment for Acute Bronchitis or Acute Cough in Patients Without Underlying Pulmonary Disease? A Systematic Review
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Original Research
Answering Family Physicians’ Clinical Questions Using Electronic Medical Databases
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Original Research
Assessing Guidelines for Use in Family Practice
Q&A
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Q&A
Is sildenafil (Viagra) an efficacious treatment for sexual arousal disorder in premenopausal women?
Caruso S, Intelisano G, Lupo L, Agnello C. Premenopausal women affected by sexual arousal disorder treated with sildenafil: A double blind, cross-...
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Q&A
In patients with heart disease, is the benefit of lipid-lowering therapy with statins similar in older patients to that in younger patients?
Hunt D, Young P, Simes J, et al. Benefits of pravastatin on cardiovascular events and mortality in older patients with coronary heart disease are...
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Q&A
Is early cardioversion of atrial fibrillation, facilitated by transesophageal echocardiography, safe and effective?
Weigner MJ, Thomas LR, Patel U, et al. Early cardioversion of atrial fibrillation facilitated by transesophageal echocardiography: short-term...
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Q&A
Does estrogen/progestin therapy in postmenopausal women decrease their risk of fracture?
Cauley JA, Black DM, Barrett-Connor E, et al. Effects of hormone replacement therapy on clinical fractures and height loss: the Heart and Estrogen...
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Q&A
Can helical computerized tomography be used alone to aid in the diagnosis of patients with suspected pulmonary embolism?
Perrier A, Howarth N, Didier D, et al. Performance of helical computed tomography in unselected outpatients with suspected pulmonary embolism. Ann...
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Q&A
Does a change to long-acting antianginals provide better symptom control, treatment satisfaction, and quality of life?
Spertus JA, Dewhurst T, Dougherty CM, Nichol P. Testing the effectiveness of converting patients to long-acting antianginal medications: the...
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Q&A
Is a 2-day course of oral dexamethasone more effective than 5 days of oral prednisone in improving symptoms and preventing relapse in children with acute asthma?
Qureshi F, Zaritsky A, Poirier MP. Comparative efficacy of oral dexamethasone versus oral prednisone in acute pediatric asthma. J Pediatr 2001;...
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Q&A
Is breast self-examination an effective screening measure for breast cancer?
Baxter N, with the Canadian Task Force on Preventive Health Care. Preventive health care, 2001 update: should women be routinely taught breast...