Applied Evidence
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Applied Evidence
Evaluation of the Patient with Dyspepsia
Clinical Inquiries
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Clinical Inquiries
Are antibiotics effective for travelers’ diarrhea?
Evidence-based answer: Randomized controlled trials have shown that use of quinolone antibiotics for 3 days reduces the length of an episode of...
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Clinical Inquiries
What is the differential diagnosis of an elevated alkaline phosphatase (AP) level in an otherwise asymptomatic patient?
Evidence-based answer: There is no evidence regarding the differential diagnosis of an elevated AP level in a primary care asymptomatic population...
Commentary
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Commentary
Obesity Management in Primary Care Changing the Status Quo
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Commentary
Multiple-Problem patient visits
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Commentary
A new suicide
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Commentary
The silver lining
Original Research
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Original Research
Improving Depression Care: Barriers, Solutions, and Research Needs
Potential solutions for barriers to improved organization of care of depressive illness were identified.
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Original Research
Treating Depressive Disorders: Who Responds, Who Does Not Respond, and Who Do We Need to Study?
Numerous studies show that pharmacotherapy and psychotherapy are efficacious and effective in treating depression.
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Original Research
Beta-Blockers to Reduce Mortality in Patients with Systolic Dysfunction A Meta-Analysis
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Original Research
Randomized Placebo-Controlled Trial of Long-Term Treatment with Sibutramine in Mild to Moderate Obesity
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Original Research
Weight Management: What Patients Want from Their Primary Care Physicians
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Original Research
The Patient’s Perspective of Irritable Bowel Syndrome
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Original Research
Improving Care for Depression in Organized Health Care Systems A Conference Report
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Original Research
Treating Depression in Primary Care: Practice Applications of Research Findings
Q&A
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Q&A
Are antibiotics appropriate for the treatment of acute sinusitis in adults?
Snow V, Mottur-Pilson C, Hickner JM. Principles of appropriate antibiotic use for acute sinusitis in adults. Ann Intern Med 2001; 134:495-97.
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Q&A
How accurate is a second-trimester prenatal ultrasound in the diagnosis of Down syndrome?
Smith-Bindman R, Hosmer W, Feldstein VA, Deeks JJ, Goldberg JD. Second-trimester ultrasound to detect fetuses with Down syndrome. JAMA 2001; 285:...
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Q&A
Should patients with nonulcer dyspepsia and Helicobacter pylori be treated with antibiotics?
Laine L, Schoenfeld P, Fennerty B. Therapy for Helicobacter pylori in patients with nonulcer dyspepsia: a meta-analysis of randomized controlled...
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Q&A
Does treatment with topical metronidazole improve seborrheic dermatitis?
Parsad D, Pandhi R, Negi KS, Kumar B. Topical metronidazole in seborrheic dermatitis: a double-blind study. Dermatology 2001; 202:35-37.
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Q&A
What is the clinical utility of obtaining a folate level in patients with macrocytosis or anemia?
Robinson AR, Mladenovic J. Lack of clinical utility of folate levels in the evaluation of macrocytosis or anemia. Am J Med 2001; 110:88-90.
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Q&A
Can a clinical decision aid be useful in determining when to discontinue in-hospital cardiac resuscitation?
Van Walraven C, Forster AJ, Parish DC, et al. Validation of a clinical decision aid to discontinue in-hospital cardiac arrest resuscitations. JAMA...
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Q&A
Does hormone replacement therapy (HRT) improve cognitive function or either delay or prevent dementia in postmenopausal women?
LeBlanc ES, Janowsky J, Chan BKS, Nelson HD. Hormone replacement therapy and cognition: systematic review and meta-analysis. JAMA 2001; 285:1489-...
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Q&A
Can 2 screening questions accurately detect alcohol and other drug abuse in the primary care setting?
Brown RL, Leonard T, Saunders LA, Papasouliotis O. A two-item conjoint screen for alcohol and other drug problems. J Am Board Fam Pract 2001; 14:...