CONCLUSION POTS most often presents as OI, which is why investigation of OI should include consideration of POTS as part of the differential diagnosis. Untreated, the symptoms of POTS can prevent patients from participating in normal life activities, including recreation, school, and work, leading to dysfunction, disability, and depression.7 A prompt diagnosis, confirmed by tilt-table testing, will expedite appropriate referral, ancillary testing, and treatment. Optimal therapy has not been established, yet individualized patient education, along with the development of a personalized program to alleviate symptoms, will provide patients with a sense of hope and control over the syndrome. This approach will enable patients and their families to manage the condition and optimize their quality of life.
The author would like to thank Michael Whitehead, DHSc, MPAS, PA-C, DFAAPA, an adjunct professor at A. T. Still University in Mesa, Arizona, for his input on this article.