Clinical Review

Boy, 10, With Knee Pain

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At this writing, the patient was scheduled for his first prosthetic fitting, and he had nearly completed his chemotherapy. His outlook is very promising.

Conclusion
TOS is a rare, aggressive subtype of OS but the most common primary malignant bone tumor of childhood. In the past, outcomes in patients treated with surgery alone were poor. With the advent of chemotherapy and the combination of medical and surgical treatment, TOS-associated mortality has continued to decline. There is no significant difference in outcomes among the available surgical options, but limb-salvage surgical procedures usually offer patients much better function and quality of life. The most important consideration is early diagnosis followed by immediate treatment.

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