The Challenges of Normal Pressure Hydrocephalus: A Case-Based Review

EPIDEMIOLOGY
The prevalence of iNPH has been estimated at 21.9 cases per 100,000 persons.⁶ It occurs primarily in individuals older than age 60⁶ and occurs more frequently with increasing age, as shown in a recent report in which the prevalence of probable iNPH was 0.2% in those ages 70 to 79 and 5.9% in those ages 80 and older.⁷ Based on these numbers, the authors estimated that approximately 700,000 Americans older than 70 may have iNPH. It is a rare cause of dementia among the population with dementia onset after age 65 (“senile onset”). No gender or racial/ethnic differences have been reported.

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