Lipid Disorders
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Roche Blood Test for Lp(a) Designated Breakthrough Device
Device intended to identify adults with elevated Lp(a) levels, and who may benefit from therapy, is granted breakthrough status.
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Statins Show ‘Remarkable’ CVD Benefit in Oldest Patients
Findings support prescribing statins for primary prevention but an expert says he won’t change practice before seeing results of the PREVENTABLE...
Conference Coverage
Statin Use May Extend Life for Early Breast Cancer Patients
Data from an emulation trial drew attention with a simple strategy that might improve outcomes for patients with breast cancer.
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What Health Risks Do Microplastics Pose?
The way micro- and nanoplastics may influence cellular functions and induce stress responses is not yet well understood.
Commentary
Is Red Meat Healthy? Multiverse Analysis Has Lessons Beyond Meat
A specification curve analysis of a dataset provides a much broader picture; in the case of red meat, you see some significant results, but the...
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Metabolic Dysfunction–Associated Steatotic Liver Disease Plus HIV Ups Risk for CVD but Not Liver Disease
Compared with MASLD without HIV, the overall 5-year survival was significantly lower in MASLD with HIV, likely becuase of comorbidities.
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Novel PCSK9 Inhibitor Reduced LDL by 50%
Study finds new PCSK9 inhibitor cut LDL in half after a year, with monthly small-volume injection.
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Early Olezarsen Results Show 50% Reduction in Triglycerides
Antisense treatment that inhibits ApoC-III expression can significantly reduce triglyceride, trial finds.
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Magnesium and Metabolic Syndrome: Any Connection?
Chronic hypomagnesemia may play a role in the pathogenesis of metabolic disorders.
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Statins Tied to Lower Mortality, Even With Comorbid Dementia
“It may be time to reconsider the broad recommendations to avoid or deprescribe statins in nursing home residents.”
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Phase 2 Results: Zerlasiran siRNA Drug Lowers Lp(a) by 90%
At 36 weeks, siRNA reduced Lp(a) from baseline when compared to placebo, says company.