Breast Cancer
News
A Perfect Storm: The current climate in breast cancer
This five-part series explores the factors that contribute to racial survival disparity in breast cancer and proposes interventions for change.
Conference Coverage
Late risks of breast cancer RT are higher for smokers
Key clinical point: Receipt of radiation therapy had little effect on risks among nonsmokers, but increased the risk of lung cancer and cardiac...
News
BRCA mutation predicts neoadjuvant therapy benefit but is not strongly prognostic
Key clinical point: BRCA1/2 mutation in triple-negative breast cancer is predictive but only weakly prognostic. Major finding: Patients with a...
News
Pembrolizumab shows promise in PD-L1–positive breast cancer
Key clinical point: Pembrolizumab appears safe and modestly active for treatment of ER-positive, HER2-negative advanced breast cancer that...
News
‘Fear and ignorance’ drive rise in bilateral mastectomy
Current trends in surgical treatment of early-stage breast cancer.
News
Buparlisib overcomes endocrine resistance in hormone receptor–positive breast cancer
Key clinical point: Buparlisib modestly improves progression-free survival among women with progressive hormone receptor–positive, HER2-negative...
News
Final follow-up of BCIRG-006 shows important cardiac safety differences
An adjuvant trastuzumab-based, nonanthracycline regimen for early HER2-positive breast cancer offers important cardiac safety benefits over the...
News
DNA-mutating enzyme is implicated in tamoxifen resistance
Key clinical point: A high level of APOBEC3B expression in estrogen receptor–positive breast cancer is a marker for tamoxifen resistance. Major...
News
Can aspirin prevent breast cancer?
Aspirin use protects against a known intermediate biomarker of breast cancer risk in a dose-dependent fashion.
Conference Coverage
VIDEO: Dr. Hope S. Rugo discusses immunotherapy, neoadjuvant treatment highlights
Dr. Hope S. Rugo shared her insights on breast cancer research presented at the San Antonio Breast Cancer Symposium.