News
Common Crohn’s Immune Response to Gut Bacteria Suggests Therapeutic Target
Nearly half of patients with CD had a strong IgG immune response targeting a specific bacterial peptide in the Lachnospiraceae flagellin...
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Liquid Fasting Mitigates Negative Pre-Surgery Impact of Semaglutide
Analysis showed a 6% absolute increase in retained gastric contents in the semaglutide group compared with controls.
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MASH: Experts Offer Noninvasive Cutoffs for Prescribing Resmetirom
This guidance document allows clinicians to use a variety of NITs to start and monitor resmetirom therapy.
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Family Medicine–Led Obstetric Units Achieve Lower C-Section Rates, Better Safety Culture
Family medicine may be the most rational — and widely available — specialty to close gaps in obstetric care.
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Should First-Line Dual Checkpoint Blockade Be Used for NSCLC With Specific Mutations?
These findings are drawn from a post hoc analysis of phase 3 data and are backed up by cell line and mouse data revealing clear mechanisms of...
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MASLD Healthcare Costs Climbing Fast in Canada
Over 90% of the healthcare costs for MASLD patients were attributed not to liver disease itself but to the management of associated comorbidities...
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Vonoprazan Offers PPI Alternative for Heartburn with Non-Erosive Reflux
Patients treated with vonoprazan 10 mg and 20 mg showed a significant improvement in heartburn-free days compared to placebo.
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Celiac Screening in Kids Appears Cost-Effective
If screening strategies are deemed feasible by clinicians and patients, then implementation in routine care is needed.
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Low Follow-up of Abnormal Urine Proteinuria Dipstick Tests in Primary Care
These findings expose a broad gap in screening for chronic kidney disease, which is especially concerning since newer kidney-protecting agents are...
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Severe Maternal Morbidity Three Times Higher in Surrogate Gestational Carriers
These findings suggest that more work is needed to ensure careful selection of gestational carriers.
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Reducing Biologic Discontinuation Among Pediatric Crohn’s Patients
The reasons behind biologic discontinuation in the pediatric CD population have been poorly characterized, prompting the present study.
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Study Questions Relationship Between Crohn’s Strictures and Cancer Risk
Malignant strictures were more common among older patients with longer disease duration and frequent obstructive symptoms.
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Subcutaneous Infliximab Beats Placebo for IBD Maintenance Therapy
The safety profile of the infliximab biosimilar was comparable with that of IV infliximab, with no new safety concerns emerging during the trials...
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Should All Patients With Early Breast Cancer Receive Adjuvant Radiotherapy?
Researchers analyzed data from 589 patients with early breast cancer who were randomized to receive either high-dose or no radiotherapy.
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Do Clonal Hematopoiesis and Mosaic Chromosomal Alterations Increase Solid Tumor Risk?
Researchers analyzed whole genome sequencing data from 10,866 women in the WHI to explore possible associations between CHIP, mCA, and solid...