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Statins tied to lower ICH risk regardless of bleed location
A large new case-control study has shown a reduced risk of both lobar and nonlobar intracerebral hemorrhage with statin use, providing reassurance...
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Analysis suggests CV benefits for some antioxidant supplements
“Identifying the optimal mixture of micronutrients is important, as not all are beneficial.”
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Lp(a) tied to more early CV events than familial hypercholesterolemia
Higher levels of lipoprotein(a) are associated with risk similar to that seen with familial hypercholesterolemia, but with risk starting as low as...
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No benefit of rivaroxaban in COVID outpatients: PREVENT-HD
PREVENT-HD joins a long list of smaller trials also showing no benefit of anticoagulation in nonhospitalized COVID-19 patients.
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Four-drug combo gets BP down in one step: QUARTET-USA
The combination product containing quarter doses of four different drugs reduced blood pressure by almost 5 mm Hg more than a standard dose of one...
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New trial suggests CV benefit with EPA: RESPECT-EPA
The open-label trial could add some support to findings from the REDUCE-IT study, which showed a reduction in cardiovascular events with high-dose...
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Diuretic agents equal to prevent CV events in hypertension: DCP
Cardiovascular events were nearly identical with two different hypertension drugs in the randomized Diuretic Comparison Project trial.
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Combo thrombolytic approach fails to reduce ICH in stroke
Although there were promising signs of a potential reduced bleeding risk in intracranial hemorrhage, the DUMAS study showed no benefit on the...
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Intensive BP lowering harmful in acute ischemic stroke: ENCHANTED2/MT
“This result is not what we expected, but it is a definitive result and gives us a lower safety margin for blood pressure in acute ischemic stroke...
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Collateral flow flags stroke patients for late thrombectomy
The MR CLEAN-LATE trial shows patients selected for thrombectomy on the presence of collateral flow had a greater chance of a better functional...
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SMART-CHOICE 3-year results support dropping aspirin after PCI
The antiplatelet strategy after PCI is currently shifting to reduce the duration of DAPT.
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Aspirin primary prevention benefit in those with raised Lp(a)?
A new analysis of the ASPREE primary prevention trial of aspirin has shown a net clinical benefit in those with genotypes associated with raised...
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Cumulative blood pressure load: A better predictor of CV events?
Cumulative systolic BP load, calculating the magnitude and duration of hypertension from serial measures, may provide better prediction of major...
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Patisiran benefits ATTR amyloidosis with cardiomyopathy: APOLLO-B
More details of the positive results with the RNAi therapeutic on functional capacity and quality of life were reported.
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Artificial sweeteners linked to higher CV event risk
The first study to include artificial sweetener from all sources, not just drinks, may increase concerns about these agents. But not all are...