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Vertebral fractures still a risk with low-dose oral glucocorticoids for RA
Vertebral, not other, osteoporotic fractures were increased in current versus past users of low-dose steroids in a retrospective cohort study.
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Pharmacovigilance data implicate three new drugs in ANCA-associated vasculitis
Mirabegron, sofosbuvir, and nintedanib join a list of 12 other drugs that have been linked to an overreporting of drug-associated ANCA vasculitis...
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TNF inhibitors have delayed effect on spondyloarthritis radiographic progression
It could take 2-4 years before plain radiographs show any sign of a benefit on the spine or sacroiliac joints.
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Mavrilimumab may aid severe COVID-19 recovery
The granulocyte/macrophage-colony stimulating factor (GM-CSF) blocker reduced the need for mechanical ventilation and death by day 29 versus...
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Patients with RA on rituximab at risk for worse COVID-19 outcomes
Risk mitigation strategies such as social distancing and wearing masks, especially indoors, remain important for people being treated with...
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GRAPPA refines recommendations on psoriatic disease treatment
Biosimilars, Janus kinase inhibitors, and interleukin-23 inhibitors will feature in the 2021 update.
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BEAT-LUPUS: Belimumab after rituximab delays severe flares
Results from a phase 2b trial are “clearly encouraging” and “support the hypothesis that BAFF [B-cell–activating factor] can drive flares after...
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EULAR COVID-19 recommendations set for update
Conclusions drawn from a systematic literature review largely appear to reinforce the recommendations that have already been made but need further...
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Rituximab’s serious infection risk in ANCA-vasculitis allayed by antibiotic use
Co-use of co-trimoxazole decreased the risk for infection, which remains high in patients with vasculitis who are treated with rituximab.
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Multiple studies highlight pandemic’s impact on patients with rheumatic disease
From the Europe-based REUMAVID study to the United Kingdom’s CONTAIN study, some common themes are emerging, with lessons to be learned for future...