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Tocilizumab preserves lung function in systemic sclerosis
MADRID – The results of the focuSSced phase 3 study showed a significantly lower proportion of tocilizumab- than placebo-treated patients...
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Refractory RA responds to vagus nerve stimulation
MADRID – Pilot trial of a vagus nerve stimulator device shows relative safety and signs of efficacy over 12 weeks.
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Systemic sclerosis gastrointestinal symptoms helped by gut microbiota transplant
MADRID – Transplanting human intestinal microbiota into adult patients with limited systemic sclerosis improved gastrointestinal symptoms.
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Antibody hierarchy may drive development of SLE vs. antiphospholipid syndrome
MADRID – Specific antiphospholipid antibodies have differing influences on the manifestations of two important autoimmune diseases.
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Treat-to-target slowly emerging in axial spondyloarthritis
MADRID – While randomized trial data are awaited, observational evidence and expert opinion support the strategy in axial spondyloarthritis.
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Rituximab serious infection risk predicted by immunoglobulin levels
Retrospective study findings suggest measuring immunoglobulin levels at baseline and before each rituximab cycle to identify patients at risk of...
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Could biosimilar switchbacks due to ‘inefficacy’ be subjective?
BIRMINGHAM, ENGLAND – Switching back to an original tumor necrosis factor inhibitor for rheumatoid arthritis might be subject to patient factors...
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Proinflammatory diets up rheumatoid arthritis risk
BIRMINGHAM, ENGLAND – There was a significant association between the baseline Dietary Inflammatory Index score and subsequent development of RA...
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High multimorbidity in axial spondyloarthritis
BIRMINGHAM, ENGLAND – Many patients with axial spondyloarthritis have other medical conditions, such as depression and fibromyalgia, which may...
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Rheumatoid arthritis treatment less aggressive, not less favorable in older adults
BIRMINGHAM, ENGLAND – Patients with RA aged 75 or older were less likely to receive initial intensive therapy but were seen sooner than their...
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Methotrexate does not cause rheumatoid interstitial lung disease
BIRMINGHAM, ENGLAND – Data from two early RA cohorts reassure that methotrexate does not cause interstitial lung disease.
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Walk-in ultrasound helps to avoid unnecessary steroids for giant cell arteritis
BIRMINGHAM, ENGLAND –
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Intradermal etanercept improves discoid lupus
BIRMINGHAM, ENGLAND – Intradermal delivery of etanercept could be a novel way to treat patients with discoid lupus erythematosus (DLE).
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Experts agree on optimal use of MRI in axSpA
BIRMINGHAM, ENGLAND – Expert recommendations give guidance on how to standardize the use of MRI to diagnose axial spondyloarthritis.
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Higher infection risk in RA seen with high blood biologic levels
BIRMINGHAM, ENGLAND – Monitoring biologic blood levels may have potential for lowering infection risk in rheumatoid arthritis.