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One VA Cancer Pathway to Rule Them All?
The US Department of Veterans Affairs (VA) has developed clinical pathways to guide its clinicians through cancer...
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Telitacicept shows efficacy, safety in methotrexate-resistant RA
The investigational drug’s ACR 20 response rate was typical for RA biologic treatments, and the trial’s Chinese patient population didn’t include...
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Novel blood test can detect RA
An experimental assay detects epigenetic features within the unique patterns and sizes of cell-free DNA found in blood, but is it better than...
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IV secukinumab, alternative to self-injections, reaches primary endpoints in PsA, axSpA
Two phase 3 trials of the recently approved IV formulation of secukinumab showed its efficacy versus placebo in treating psoriatic arthritis and...
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Physician’s dispute with Mayo Clinic raises free speech, academic freedom concerns
“Joyner said he’s ‘frustrated’ with the NIH’s ‘bureaucratic rope-a-dope,’ calling the agency’s guidelines ‘a wet blanket.’ ”
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Study takes fine-grained look at MACE risk with glucocorticoids in RA
The level of risk for MACE rose with the dose, duration, and recency of GC use, and risk increased significantly at prednisone-equivalent doses as...
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Apremilast beats placebo in early PsA affecting few joints
Phase 4 trial offers insight into efficacy in patients whose mild cases have gotten less research attention.
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FDA’s Project Optimus aims to transform early cancer research
Q & A with an expert on how the FDA’s Project Optimus targets toxicity and how it could spell the end of traditional dose-escalation trials....
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Caution raised on reduced-dose steroids in rare vasculitides GPA, MPA
A real-world analysis finds that some patients who receive reduced-dose glucocorticoids may have a higher risk of poor outcomes.
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CPPD nomenclature is sore subject for gout group
G-CAN hopes to standardize terminology and finally oust ‘pseudo’ vernacular.
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Gout: Studies support early use of urate-lowering therapy, warn of peripheral arterial disease
Urate-lowering drugs might be OK early on; gout may boost peripheral arterial disease.
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T-cell cancers: CAR T therapy to the rescue?
Trials are small and incomplete, but CAR T-cell therapy has yielded promising early results in treating T-cell blood cancers.
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84-year-old MD contests employer’s mandatory cognitive tests for older docs
According to the lawsuit, the hospital illegally required neuropsychological and eye examinations of physicians aged 70 or older who sought to...
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How Does Military Service Impact Cancer Risk? It’s Complicated
While it’s extremely difficult to link cancer rates to military service, researchers are starting to get some initial...
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MS, DMTs, and pregnancy: Beware of over-caution regarding treatment
Don’t be too quick to stop therapy or too slow to restart it, researcher tells ECTRIMS audience.