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Is Pimavanserin a Better Option for Parkinson’s Psychosis?
Pimavanserin yielded significant improvement across all parameters of efficacy without worsening motor symptoms and was very well tolerated.
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Clozapine and Respiratory Infection Risk: What to Know
Although antipsychotic use was not linked to higher rates of mild infection, it was linked to an increased risk for COVID-19 hospitalization in...
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Investigational Med for Tourette Syndrome Promising
Ecopipam reduced the primary endpoint of tic severity scores by 30% compared with placebo among 149 patients in the 12-week, phase 2b D1AMOND...
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Nighttime Outdoor Light Pollution Linked to Alzheimer’s Risk
Among people aged 65 years or older, Alzheimer’s disease prevalence was more strongly associated with nightly light pollution exposure than with...
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New Biological Pathway May Explain BPA Exposure, Autism Link
Silencing a key enzyme, aromatase, that controls neurohormones and is especially important in fetal male brain development, may be associated with...
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More Evidence PTSD Tied to Obstructive Sleep Apnea Risk
Older veterans with PTSD are at increased risk for OSA, study finds.
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Commonly Used Meds Tied to Lower Risk for Brain Aneurysm Rupture
Five drugs reduced the risk. Four other drugs increased the risk.
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Suicide in Surgeons: The Heavy Toll of a High-Stakes Career
Medical professionals are at increased suicide risk, with 6.3% of surgeons considering suicide, compared to 4.9% for the average US adult.
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Is Meningitis a Risk Factor for Trigeminal Neuralgia? New Data
In multivariate analysis, the odds of meningitis were threefold higher in patients admitted with trigeminal neuralgia than in matched controls...
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Diabetes/Weight Loss Med Linked to Repeat Spinal Surgery
Medical complications were driven by higher rates of urinary tract and acute kidney infections, not by surgical complications in the semaglutide...
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Recount of FOURIER data finds higher mortality with evolocumab; trialists push back
A readjudication of mortality data from the FOURIER trial by outside researchers concludes CV death was higher with evolocumab than originally...
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Survival varies widely for cardiac arrests in U.S. cath labs
These events warrant their own dedicated study, new evidence, and specific guidance, observers say.
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High lipoprotein(a) levels plus hypertension add to CVD risk
A new analysis illustrates, for the first time, a significant interaction between Lp(a) and hypertension in the primary prevention of...
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Vitamin D fails to stave off statin-related muscle symptoms
A substudy of the VITAL trial provides the first randomized data examining the effect of the popular supplement on muscle symptoms in statin users...
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Baxdrostat slashes BP in resistant hypertension: BrigHTN
The novel agent lowers aldosterone activity without the off-target inhibition of cortisol synthesis that has thwarted previous drug candidates,...