News
Cord blood/placental cell combo induces rapid immune recovery
MONTREAL – The probability of 1-year survival in children with severe diseases requiring stem cell transplants was 81%.
News
Routine surveillance adds cost but little benefit following a pediatric tumor
MONTREAL – It can be a tough sell to worried patients or their caregivers, but surveillance imaging in children with a history of some treated...
News
Treatment-related hypertension, kidney injury are undertreated in kids with leukemia
MONTREAL – Chemotherapy-related hypertension and acute kidney injury can go unrecognized in children and young adults with ALL and AML.
News
Modifying CAR-T with IL-15 improved activity in glioma models
Adding an immunostimulatory cytokine to CAR-T improved the adaptive immunotherapy’s activity against aggressive pediatric brain malignancies.
News
Palbociclib/fulvestrant works in Asians with HR+/HER2– breast cancer too
In the PALOMA-3 trial, palbociclib plus fulvestrant outperformed fulvestrant with placebo.
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Racial disparities in ovarian cancer care persist until death
Care for black and Hispanic women with ovarian cancer misses the mark on many quality care measures at the end of life.
News
Only some genes count in breast cancer panels
Germline variants in PALB2 were associated with a more than sevenfold greater risk for breast cancer.
Video
VIDEO: Residual cancer burden may be better outcome measure than pCR
MIAMI BEACH – The Food and Drug Administration has accepted pathological complete response rate (pCR) as a surrogate endpoint for disease-free and...
Video
VIDEO: It’s too early to give up on immunotherapy for breast cancer
MIAMI BEACH – Breast cancer is less immunogenic that melanoma, bladder cancer, lung cancer, and other malignancies that have responded well to...
Video
VIDEO: What’s new with HER2-neu inhibition
MIAMI BEACH – For women with HER2-positive disease, neoadjuvant therapy with trastuzumab (Herceptin) was and is a game changer, improving...
Video
VIDEO: Registry studies reflect real patients in the real world
MIAMI BEACH – Studies using data from prospective registries provide valuable insights for investigators into diseases of real patients in real-...
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VIDEO: HER2+ patients may do fine with local therapies alone
MIAMI BEACH – Unquestionably, the advent of human epidermal growth factor receptor-2 (HER2) inhibitors has dramatically improved long-term...
Video
VIDEO: Resistance to endocrine therapy a moving target
MIAMI BEACH – Dr. William J. Gradishar discusses strategies for combating resistance to endocrine ablative therapy in a video interview.
News
Soluble PD-L1 correlates with melanoma outcomes
ORLANDO – Can soluble PD-L1 be used to predict malignant melanoma outcomes?
News
CAR designers report high B-cell cancer response rates
A CAR-T cell construct consisting of autologous CD4-positive and CD-8 positive T cells delivered in a single infusion was associated with high...