News
Everolimus/exemestane improves PFS of ER+/HER2– breast cancer vs. everolimus alone
In this phase 2 randomized study, adding exemestane had better efficacy than did single-agent everolimus, but single-agent capecitabine appeared...
News
Avelumab does not add punch to ALK inhibitors for ALK+/– NSCLC
A combination of lorlatinib and avelumab showed good activity and acceptable safety against ALK-positive lung cancer, but no better efficacy than...
News
Geriatric assessments improve oncologist-patient communications
CHICAGO – A randomized study of community oncology centers showed that when oncologists were informed of geriatric assessment results, patient...
News
Frontline immunotherapy boosts survival in NSCLC patients
CHICAGO – For patients with NSCLC expressing PD-L1 on at least 1% of tumor, upfront pembrolizumab significantly prolonged OS with lower toxicities...
News
PI3K inhibitor/fulvestrant has modest benefit, serious toxicity in breast cancer
CHICAGO – The combination of talesib/fulvestrant extended PFS by two months, but at a cost of serious toxicities in half of the patients treated...
News
Equal treatment, equal or better prostate cancer outcomes for black men
CHICAGO - “The nihilism associated with prostate cancer in African-American men is not supported by this really interesting work.”
Video
Heading down the wrong pathway in advanced breast cancer?
CHICAGO - Dr. Harold Burstein questions whether the PI3K pathway is worth pursuing, despite positive results from SANDPIPER.
Video
Geriatric assessments enhance patient care in advanced cancer
CHICAGO - Dr. Supriya Mohile discusses study results indicating that geriatric assessments improve communication and boost patient satisfaction....
Video
Stronger abiraterone response in mCRPC seen in black men
CHICAGO – Lead study author Dr. Daniel George discusses issues surrounding access to the standard of care for advanced prostate cancer.
News
IMDC model mirrors mRCC clinical outcomes
Patients with mRCC stratified into favorable- and intermediate-risk categories had better response rates and longer survival than did poor-risk...
News
cfDNA reveals targetable mutations in pediatric neuroblastoma, sarcoma
PITTSBURGH – ‘Liquid biopsy’ of patients with genetically profiled tumors showed potentially actionable somatic mutations and copy number...
News
Pediatric cancers are on the rise
PITTSBURGH – CDC investigators detected a significant increase in pediatric cancers from 2001 through 2014, although the reasons for the rise are...
News
Multiple solid tumors targeted by concept CAR T
PITTSBURGH – Could this CAR T therapy become a viable option against pediatric solid tumors?
News
Children with Down syndrome and ALL have good outcomes today
PITTSBURGH – With better therapy and supportive care, prospects for children with Down syndrome and standard risk ALL have improved in recent...
News
Patients with CF at increased risk for GI cancers
Patients who received lung transplants for cystic fibrosis are at especially high risk for developing gastrointestinal cancers.