News
Update Coming for Thyroid Disease in Pregnancy Guidelines
- Author:
- Nancy A. Melville
Age over 30 years, having at least two prior pregnancies, and morbid obesity (body mass index [BMI] at least 40 kg/m2), will no longer...
News
Myeloma: Isa-KRd Induction Shows High MRD Responses
- Author:
- Nancy A. Melville
Interim analysis of first MIDAS trial findings shows “highest rate of response and MRD negativity to date.”
News
Daratumumab Quadruplet Supported Transplant-Ineligible MM
- Author:
- Nancy A. Melville
A phase-3 study showed that adding daratumumab to VRd yields a primary endpoint of MRD negativity in patients newly diagnosed with myeloma.
News
Myeloma: Daratumumab Plus Lenalidomide Improves MRD Outcomes
- Author:
- Nancy A. Melville
New research shows that adding daratumumab to maintenance therapy improves MRD and PFS outcomes in multiple myeloma.
News
SGLT2 Inhibitor Reduces Risk for Neurodegenerative Diseases in T2D
- Author:
- Nancy A. Melville
Those receiving SGLT2i treatment had a 21% reduced risk for all-cause dementia and a 22% reduced risk for all-cause dementia and Parkinson’s...
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After Rapid Weight Loss, Monitor Antiobesity Drug Dosing
- Author:
- Nancy A. Melville
Toxicities from excessive doses can have a range of detrimental effects; examine dosing following rapid weight loss.
News
LBCL: CAR T Benefits Both Young and Old
- Author:
- Nancy A. Melville
Evidence shows that CAR T-cell therapy yields similar survival outcomes for both older and younger patients with large B-cell lymphoma.
News
Hemophilia: Novel Tx Also Cuts Bleeding in Kids
- Author:
- Nancy A. Melville
For pediatric patients with hemophilia A, once-weekly factor VIII prophylaxis shows bleeding protection similar to that for adults.
News
What Should Be Prioritized in Managing Early Diabetes?
- Author:
- Nancy A. Melville
ADA meeting debate on what to treat first in early diabetes included obesity, glucose, remission as priorities.
News
Hemophilia: Marstacimab Sustains Long-Term Bleeding Reduction
- Author:
- Nancy A. Melville
In an interim analysis, this novel, weekly subcutaneous injection shows continued benefits in the prevention of bleeding in hemophilia A and B.
News
Pancreatic Gene Therapy: A ‘One-and-Done’ GLP-1 Treatment?
- Author:
- Nancy A. Melville
A single-dose pancreatic gene therapy may compare with GLP-1 effect, a mouse model study finds.
News
DLBCL: Glofitamab Plus Chemo Boosts Survival
- Author:
- Nancy A. Melville
The bispecific antibody glofitamab, combined with chemotherapy, significantly improves overall survival in second-line treatment of DLBCL.
News
APL: Should Chemo-Free Regimen Become New Standard?
- Author:
- Nancy A. Melville
Fresh data indicates that the benefits of a chemo-free regimen also extend to the treatment of high-risk acute promyelocytic leukemia.
News
Myeloma: First-In-Class ADC Regimen Yields Key Benefits
- Author:
- Nancy A. Melville
Patients with relapsed/refractory multiple myeloma show significant improvements in PFS when treated with an antibody-drug conjugate.
News
CML: Asciminib Bests Standard TKIs as Frontline Therapy
- Author:
- Nancy A. Melville
For CML, this potent, highly selective TKI significantly improves molecular responses, reduces discontinuations versus standard TKIs.