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    Michael E. Pichichero, MD

    News

    Anticipated Effects of Pneumococcal Vaccines on Otitis

    Author:
    Michael E. Pichichero, MD
    Publish date: October 7, 2024

    As we commence use of PCV15 and PCV20 in the United States, our data provide insights regarding estimation of the projected effects of these...

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    News

    Predicting and Understanding Vaccine Response Determinants

    Author:
    Michael E. Pichichero, MD
    Publish date: June 13, 2024

    Cytokines measured in nasopharyngeal secretions in the neonatal period may predict vaccine response.

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    News

    Microbiome Impacts Vaccine Responses

    Author:
    Michael E. Pichichero, MD
    Publish date: January 30, 2024

    A major factor affecting immune development is the microbiome of the newborn and the first 100 days of life.

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    News

    Laissez-faire

    Author:
    Michael E. Pichichero, MD
    Publish date: November 6, 2023

    While reducing antibiotic resistance is an important concern at a patient and community level, we should not become complacent about the risks to...

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    News

    Profile of respiratory bacteria in children younger than 6 months

    Author:
    Michael E. Pichichero, MD
    Publish date: June 12, 2023

    Researchers provide heretofore unreported contemporary data in a highly PCV13-immunized, community-based child population in the United States.

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    Opinion

    Young children quickly outgrow the need for ear tubes

    Author:
    Michael E. Pichichero, MD
    Publish date: February 9, 2023

    Children having several ear infections in a short time does not predict that they will have a similar number of ear infections in the future.

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    Opinion

    Immunity debt and the tripledemic

    Author:
    Michael E. Pichichero, MD
    Publish date: December 7, 2022

    The significant reduction in respiratory illness during the COVID-19 epidemic we and others observed resulted in a large pool of children who did...

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    Opinion

    Acute otitis media pneumococcal disease burden in children due to serotypes not included in vaccines

    Author:
    Michael E. Pichichero, MD
    Publish date: August 15, 2022

    In pneumococcal conjugate–vaccinated populations, vaccine pressure and antibiotic resistance drive PCV serotype replacement with nonvaccine...

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    Opinion

    Antibiotics use and vaccine antibody levels

    Author:
    Michael E. Pichichero, MD
    Publish date: May 1, 2022

    Our study adds new reasons to be cautious about overprescribing antibiotics on an individual child basis because an adverse effect extends to...

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    Opinion

    Effect of COVID-19 pandemic on respiratory infectious diseases in primary care practice

    Author:
    Michael E. Pichichero, MD
    Steven A. Schulz, MD
    Publish date: October 12, 2021

    Public health measures to prevent the spread of SARS-CoV-2 included a concurrent reduction in risk for children to acquire and spread respiratory...

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    Opinion

    Respiratory infection– and asthma-prone children

    Author:
    Michael E. Pichichero, MD
    Publish date: July 12, 2021

    The pathogenesis, development, severity, and clinical outcomes of respiratory infections are largely dependent on the resident composition of the...

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    Opinion

    Myth busting: SARS-CoV-2 vaccine

    Author:
    Michael E. Pichichero, MD
    Publish date: March 10, 2021

    The mRNA and replication-defective DNA vaccines never interact with your DNA. They cannot alter your DNA.

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    Opinion

    Understanding messenger RNA and other SARS-CoV-2 vaccines

    Author:
    Michael E. Pichichero, MD
    Publish date: December 14, 2020

    Technological advances make these new and revolutionary vaccines a reality.

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    Opinion

    A young family consults with a doctor by using a digital tablet

    COVID-19: A primary care perspective

    Author:
    Steven A. Schulz, MD
    Michael E. Pichichero, MD
    Publish date: July 15, 2020

    Continued education, cooperation, and adaptation will be needed in the months ahead.

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    Opinion

    Why is AOM frequency decreasing in the pneumococcal conjugate vaccine era?

    Author:
    Michael E. Pichichero, MD
    Publish date: January 10, 2020

    Changing recommendations and campaigns to reduce unnecessary and inappropriate antibiotic use appear to be some...

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