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ADHD rates holding steady in U.S. children
The estimated ADHD prevalence remains “high” and “further investigation is warranted to assess potentially modifiable risk factors and provide...
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FDA denies approval for patisiran in ATTR cardiomyopathy, despite panel nod
The FDA indicated in the letter that the clinical meaningfulness of patisiran’s treatment effects for the cardiomyopathy of ATTR amyloidosis have...
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Redefining CVD risk: Cardiovascular-kidney-metabolic (CKM) syndrome
“Clearly defining the patient with CKM syndrome, and providing new approaches for CKM syndrome staging and risk prediction, will help health care...
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MASLD linked to increased risk for various clinical outcomes
The disease significantly raises the risk for cardiovascular, metabolic, oncologic, and other outcomes.
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A new clue into the cause, spread of Parkinson’s disease?
The study demonstrates “for the first time how damaged mitochondrial DNA can underlie the mechanisms of PD initiation and spread in brain,” the...
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Early-onset NAFLD tied to higher cancer risk
Among adults younger than 45 at NAFLD onset, cancers were mainly digestive and lung cancers.
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Loneliness tied to increased risk for Parkinson’s disease
The association between loneliness and incident PD was not moderated by sex, age, or polygenetic risk score.
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USPSTF should reconsider recommendation to lower mammogram age: Experts
The benefit is arguably small, while the harms appear quite significant.
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Jury out on how tea drinking influences colorectal cancer risk
Tea drinking may reduce the risk for colorectal cancer by 24%, but the estimate is uncertain.
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Vegetarian diets tied to lower risk for some GI cancers
“The results of this systematic review indicate that adherence to vegetarian diets can reduce the risk of gastrointestinal cancers, compared with...
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FDA OKs subcutaneous vedolizumab for UC maintenance therapy
The safety profile of subcutaneous vedolizumab was “generally consistent” with the intravenous form of the drug, with the addition of injection-...
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ChatGPT may aid decision-making in the ED for acute ulcerative colitis
Chatbot provided a detailed answer depicting severity of every variable of the criteria and an overall severity classification.
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Real-world data confirm efficacy of dupilumab in severe EoE
Researchers conducted a retrospective cohort study of 46 patients with severe, treatment-refractory fibrostenotic EoE.
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Many young people stop ulcerative colitis maintenance treatment, risking relapse
Globally, the incidence of UC is increasing fastest in younger populations. It’s estimated that up to 30% of individuals with UC are diagnosed in...
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Omitting sentinel lymph node biopsy safe for some early breast cancers
Data support “the argument that sentinel node positivity is not, in and of itself, a critical parameter that determines therapeutic plans and...