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Frontline rituximab shows long-term success in indolent lymphoma
A study with 10-year follow-up data suggests that chemotherapy can be delayed in symptomatic indolent lymphoma patients.
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AITL responds to 5-azacytidine in small series
The small study showed high response and no significant safety concerns.
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Brentuximab vendotin plus CHP meets PFS endpoint in ECHELON-2
Takeda Pharmaceuticals and Seattle Genetics announced phase 3 trial results in frontline treatment of peripheral T-cell lyphoma (PTCL).
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New mantle cell trials launching
At least four new mantle cell lymphoma trials were registered in Clinicaltrials.gov in August 2018.
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New BTK inhibitor under review in China
Zanubrutinib is being reviewed for treatment of relapsed/refractory mantle cell lymphoma.
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Blood disorders researcher is finalist for Trailblazer Prize
Dr. Daniel Bauer of Dana-Farber/Boston Children’s Cancer and Blood Disorders Center, was recognized for his research on sickle cell disease and...
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PET/CT accurately predicts MCL stage
The promising results suggest bone marrow involvement could be assessed without a biopsy.
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Ibrutinib stacks up well on safety in pooled analysis
The study looked at ibrutinib safety for CLL/SLL and MCL across four studies.
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FDA issues guidance for hemophilia gene therapy development
The agency issued three disease-specific gene therapy guidances, including for retinal disorders and rare diseases.
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Pfizer launches phase 3 gene therapy study in hemophilia B
Fidanacogene elaparvovec is an investigational gene therapy aimed at allowing hemophilia B patients to live free of routine infusions.
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Lab results may help predict complications in ALL treatment
Researchers identified factors that predict which pediatric ALL patients were likely to have a longer hospital stay after induction chemotherapy...
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Promising phase 3 results for ixazomib in multiple myeloma
The drug met the primary endpoint in a phase 3 study of maintenance therapy after stem cell transplant.
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European Medicines Agency recommends CAR T-cell approvals
The therapies must be approved by the European Commission before they can be marketed to patients.
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Bortezomib plus vorinostat shows modest response in MCL
The phase 2 trial looked at the combination in mantle cell lymphoma and diffuse large B-cell lymphoma patients.