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    Mark S. Lesney

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    Small study suggests natural HCV clearance is caused by AR3-antibody response

    Author:
    Mark S. Lesney
    Publish date: July 18, 2019

    Cross-genotype and neutralizing antibodies, especially targeting AR3, contribute to HCV clearance and long-term protection.

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    News

    Ebola outbreak: WHO/OCHA call for more aid, better security

    Author:
    Mark S. Lesney
    Publish date: July 18, 2019

    Security, public trust, and a lack of resources are significant barriers to countering the current Ebola epidemic in the Democratic Republic of...

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    News

    Patients with COPD at heightened risk for community-acquired pneumonia requiring hospitalization

    Author:
    Mark S. Lesney
    Publish date: July 11, 2019

    COPD patients were about 18 times more likely to develop community-acquired pneumonia requiring hospitalization.

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    News

    Microvascular disease: An independent and exacerbating risk factor for amputation

    Author:
    Mark S. Lesney
    Publish date: July 8, 2019

    The presence of microvascular disease plus peripheral artery disease resulted in a more than 20-fold increased risk of amputation than MVD or PAD...

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    News

    FDA panel: Continue using paclitaxel-eluting PAD devices, with caveats

    Author:
    Mark S. Lesney
    Publish date: June 21, 2019

    Although the benefits of the devices were clear, the panel felt there should be a label change to warn of the late mortality signal seen in a key...

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    Article

    FDA panel to reassess the fate of paclitaxel-coated PAD devices

    Author:
    Mark S. Lesney
    Publish date: May 22, 2019

    The FDA is requesting the panel’s input regarding the presence and magnitude of the increased mortality signal and its potential causes.

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    News

    Despite HCV cure, liver cancer-associated genetic changes persist

    Author:
    Mark S. Lesney
    Publish date: May 22, 2019

    Liver tissue from HCV-infected with and without sustained virologic response found epigenetic and gene...

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    News

    Respiratory effects may account for worse survival in women undergoing DTA and TAAA repair

    Author:
    Mark S. Lesney
    Publish date: May 14, 2019

    Women had significantly worse 5-year survival than men undergoing DTA or TAAA repair (59.7% vs. 66.2%, P...

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    News

    DOPPS participation associated with lower HCV rates in dialysis patients

    Author:
    Mark S. Lesney
    Publish date: May 8, 2019

    HCV infection decreased from 2.9 to 1.2 per 100 patient-years in countries participating in the initial phase of DOPPS.

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    News

    Higher serum leptin levels associated with PAD

    Author:
    Mark S. Lesney
    Publish date: May 8, 2019

    Serum leptin levels are positively and independently associated with PAD.

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    News

    New vascular 0 + 5 training programs yield fewer PAD cases

    Author:
    Mark S. Lesney
    Publish date: April 24, 2019

    VSFs currently perform more endovascular and open cases than their 0 + 5 IVSR counterparts for peripheral...

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    News

    Ask patients, not devices, about impact of PAD

    Author:
    Mark S. Lesney
    Publish date: April 24, 2019

    Direct assessment from patients is the best measure of the impact of PAD on patients’ symptoms, functional...

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    News

    HCC linked to mitochondrial damage, iron accumulation from HCV

    Author:
    Mark S. Lesney
    Publish date: April 24, 2019

    Mitochondrial damage and iron accumulation from HCV are linked to the development of hepatocellular carcinoma.

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    News

    Patient complications affect surgeons adversely

    Author:
    Mark S. Lesney
    Publish date: April 19, 2019

    Patient complications affect surgeons’ emotional health, and organizations must acknowledge this and develop...

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    News

    An HCV-infected population showed gaps in HBV testing, vaccination, and care

    Author:
    Mark S. Lesney
    Publish date: April 11, 2019

    A cohort of HCV-infected patients showed a high prevalence of current or past HBV infection, but with gaps in...

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