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    Mark S. Lesney, PhD

    News

    Blood group O linked to decreased risk of SARS-CoV-2 infection

    Author:
    Mark S. Lesney, PhD
    Publish date: October 15, 2020

    A retrospective analysis of all Danish individuals with a known ABO blood group tested for SARS-CoV-2 showed a lower infection risk for SARS-CoV-2...

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    News

    Study: Complications from childhood ALL and its treatment are common, but can be managed

    Author:
    Mark S. Lesney, PhD
    Publish date: October 15, 2020

    Despite survival after treatment of acute lymphoblastic leukemia, a high percentage of children suffered acute...

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    News

    Older adults with multiple myeloma face heavy burden of care

    Author:
    Mark S. Lesney, PhD
    Publish date: October 8, 2020

    Newly diagnosed older adults with multiple myeloma (MM) face a heavy burden of treatment.

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    Article

    Meta-analysis: Acalabrutinib showed better PFS and OS than other frontline CLL therapies

    Author:
    Mark S. Lesney, PhD
    Publish date: October 7, 2020

    Progression-free and overall survival improved with acalabrutinib over other chronic lymphocytic leukemia...

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    News

    Orthopedic problems in children can be the first indication of acute lymphoblastic leukemia

    Author:
    Mark S. Lesney, PhD
    Publish date: September 30, 2020

    The diagnosis of acute lymphoblastic leukemia (ALL) is often delayed because of vague presentation and normal...

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    News

    Initial response to novel agents preps MM patients for favorable transplant outcomes

    Author:
    Mark S. Lesney, PhD
    Publish date: September 24, 2020

    Triplet induction outperformed doublet in early outcomes, but later outcome differences were not statistically significant.

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    News

    Two new protein biomarkers may serve as prognostic indicators for outcomes in CLL

    Author:
    Mark S. Lesney, PhD
    Publish date: September 23, 2020

    Study also validated the prognostic value of two previously studied biomarkers.

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    News

    Low VWF levels or blood group O not linked to intracerebral hemorrhage risk

    Author:
    Mark S. Lesney, PhD
    Publish date: September 10, 2020

    Unlike some previous studies, low levels of von Willebrand Factor (VWF) and blood group O were not associated...

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    News

    Statins linked to improved survival in multiple myeloma

    Author:
    Mark S. Lesney, PhD
    Publish date: September 10, 2020

    Statin use was associated with an overall reduction of the risk of death in MM patients, including those treated...

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    News

    Oxidative stress linked to cytogenetic abnormalities in CLL

    Author:
    Mark S. Lesney, PhD
    Publish date: September 9, 2020

    Patients with B-cell chronic lymphocytic leukemia had increased serum oxidative stress markers and an imbalance...

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    News

    CSF metabolomic profile linked to cancer-related fatigue in children with ALL

    Author:
    Mark S. Lesney, PhD
    Publish date: September 8, 2020

    Cerebrospinal fluid revealed three metabolites significantly associated with cancer-related fatigue in children...

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    Opinion

    Chronicles of Cancer: A history of mammography, part 2

    Author:
    Mark S. Lesney, PhD
    Publish date: September 4, 2020

    The history of mammography is rife with controversy, enmeshed in the War on Cancer, corporate and professional interests, and the women’s rights...

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    News

    Napabucasin suppressed tumor growth in DLBCL cell lines

    Author:
    Mark S. Lesney, PhD
    Publish date: September 2, 2020

    Napabucasin suppressed tumor growth, decreased Ki67 and CD31 and increased cleaved caspase-3.

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    News

    Age, other risk factors predict length of MM survival

    Author:
    Mark S. Lesney, PhD
    Publish date: August 27, 2020

    Autologous stem cell treatment was more effective in those who developed MM at a younger age.

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    News

    Antihistamines synergistically induce CLL cell death with TK inhibitors

    Author:
    Mark S. Lesney, PhD
    Publish date: August 26, 2020

    Over-the-counter antihistamines induced synergistic cytotoxicity with TK inhibitors.

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