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    M. Alexander Otto

    M. Alexander Otto began his reporting career early in 1999 covering the pharmaceutical industry for a national pharmacists' magazine and freelancing for the Washington Post and other newspapers. He then joined BNA, now part of Bloomberg News, covering health law and the protection of people and animals in medical research. Alex next worked for the McClatchy Company. Based on his work, Alex won a year-long Knight Science Journalism Fellowship to MIT in 2008-2009. He joined the company shortly thereafter. Alex has a newspaper journalism degree from Syracuse (N.Y.) University and a master's degree in medical science -- a physician assistant degree -- from George Washington University. Alex is based in Seattle.

    News

    Drug conjugate extends life in HER2+ end-stage metastatic colorectal cancer

    Author:
    M. Alexander Otto
    Publish date: June 5, 2021

    An almost 50% response rate is “very exciting.”

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    News

    Study findings support consideration of second biopsy for transected melanomas

    Author:
    M. Alexander Otto
    Publish date: June 3, 2021

    Accurate Breslow depth is necessary for surgical decisions.

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    News

    Mohs surgery favorable as monotherapy for early Merkel cell carcinomas

    Author:
    M. Alexander Otto
    Publish date: June 2, 2021

    Small series adds to growing body of literature.

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    News

    Checkpoint inhibitors earn spot in new ESMO SCLC guidelines

    Author:
    M. Alexander Otto
    Publish date: May 17, 2021

    ESMO calls for upfront atezolizumab or durvalumab with etoposide and a platinum for stage 4 SCLC.

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    News

    Study supports intensifying chemoradiotherapy for head and neck cancer

    Author:
    M. Alexander Otto
    Publish date: May 10, 2021

    Intensifying chemoradiotherapy appeared to improve outcomes in locally advanced head and neck cancer.

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    News

    Novel hedgehog inhibitor strategies improve BCC outcomes

    Author:
    M. Alexander Otto
    Publish date: May 10, 2021

    Upfront tumor debulking seems to help.

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    News

    Checkpoint inhibitor skin side effects more common in women

    Author:
    M. Alexander Otto
    Publish date: May 6, 2021

    "Clinicians should consider these results in counseling female patients regarding an elevated risk of dermatologic adverse events."

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    News

    Lobaplatin deemed ‘promising alternative’ to cisplatin in nasopharyngeal carcinoma

    Author:
    M. Alexander Otto
    Publish date: April 30, 2021

    A lobaplatin-based regimen was as effective as a cisplatin-based regimen in a phase 3 trial.

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    News

    Survival benefit with nivolumab extends to 5 years in NSCLC

    Author:
    M. Alexander Otto
    Publish date: April 26, 2021

    Early response portends durable outcome, but the optimal duration of treatment is uncertain.

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    News

    Cell-free DNA improves response prediction in breast cancer

    Author:
    M. Alexander Otto
    Publish date: April 21, 2021

    Using cell-free DNA and MRI in combination improved prediction of pathological complete response.

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    News

    Adverse reactions to immunotherapy can appear after a year

    Author:
    M. Alexander Otto
    Publish date: April 15, 2021

    Some melanoma patients receiving anti-PD-1 immunotherapy may tolerate the drug well for months but then develop...

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    News

    Combo provides ‘broad benefit’ across NHL subtypes

    Author:
    M. Alexander Otto
    Publish date: April 12, 2021

    Adding copanlisib to rituximab improved progression-free survival, but overall survival data are not mature.

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    News

    Endometrial thickness could predict cancer, guide lymph node assessment

    Author:
    M. Alexander Otto
    Publish date: April 12, 2021

    Patients with endometrial intraepithelial neoplasia don’t need routine lymph node sampling, an investigator says.

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    News

    Negative results when immunotherapy was added to chemoradiotherapy

    Author:
    M. Alexander Otto
    Publish date: April 9, 2021

    A phase 3 trial investigating the addition of avelumab to chemoradiotherapy in patients with head and neck cancer was stopped early.

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    News

    Technique combines ‘best of both worlds’ to target lung nodules

    Author:
    M. Alexander Otto
    Publish date: April 5, 2021

    Bronchoscopic transbronchial microwave ablation proved feasible in a small study.

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    • MDedge Home
    • Cardiology
    • Clinician Reviews
    • Dermatology
    • Emergency Medicine
    • Endocrinology/Diabetes
    • Family Medicine
    • Federal Practitioner
    • Gastroenterology
    • Hematology/Oncology
    • Infectious Disease
    • Internal Medicine
    • Neurology
    • Obstetrics And Gynecology
    • Pediatrics
    • Psychiatry
    • Pulmonology
    • Rheumatology
    • Surgery