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    M. Alexander Otto, PA, MMS

    News

    FDA approves first gene therapy, betibeglogene autotemcel (Zynteglo), for beta-thalassemia

    Author:
    M. Alexander Otto, PA, MMS
    Publish date: August 17, 2022

    The one-time gene therapy represents a potential cure in which functional copies of the mutated gene are inserted into patients’ hematopoietic...

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    News

    Annual PSA screening important for Black men

    Author:
    M. Alexander Otto, PA, MMS
    Publish date: August 17, 2022

    “Given that Black men are younger at diagnosis and have worse prostate cancer survival compared with White men,” more intensive screening...

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    News

    FDA approves trastuzumab-deruxtecan for HER2-low breast cancer

    Author:
    M. Alexander Otto, PA, MMS
    Publish date: August 5, 2022

    Sixty percent of patients previously classified as having HER2-negative subtype are now considered HER2 low.

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    News

    HPV vaccination with Cervarix ‘unmasks’ cervical lesions from non-vax strains

    Author:
    M. Alexander Otto, PA, MMS
    Publish date: June 21, 2022

    The increase wasn’t enough to offset the overall benefit of vaccination when all genotypes were considered, said the researchers.

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    News

    Acetaminophen linked to diminished response to immunotherapy in cancer

    Author:
    M. Alexander Otto, PA, MMS
    Publish date: June 8, 2022

    “Commonly used medications may have a larger impact on the efficacy and toxicity of immune checkpoint blockade than historically seen with...

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    News

    Debate: Should biologics be used for milder cases of psoriasis?

    Author:
    M. Alexander Otto, PA, MMS
    Publish date: April 26, 2021

    The decision to use a biologic should hinge on how badly patients and their quality of life are affected, Dr. Langley said.

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    News

    Clearance rates higher with bimekizumab vs. secukinumab in phase 3 psoriasis study

    Author:
    M. Alexander Otto, PA, MMS
    Publish date: April 24, 2021

    As in past trials, oral candidiasis was an issue in patients taking bimekizumab.

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    News

    Bimekizumab tops adalimumab for plaque psoriasis

    Author:
    M. Alexander Otto, PA, MMS
    Publish date: April 23, 2021

    Bimekizumab “appears more effective than current options. The big question is safety.”

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    News

    Quicker fertility rebound in young women with breast cancer

    Author:
    M. Alexander Otto, PA, MMS
    Publish date: April 19, 2021

    Phase 3 results support omitting cyclophosphamide from standard chemotherapy.

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    News

    Liver transplant emerges for hepatic mets in colorectal cancer

    Author:
    M. Alexander Otto, PA, MMS
    Publish date: April 5, 2021

    Data suggest liver transplant can improve survival in colorectal cancer patients with extensive hepatic...

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    News

    Anthracycline-free neoadjuvant regimen safe, effective for TNBC

    Author:
    M. Alexander Otto, PA, MMS
    Publish date: March 8, 2021

    A taxane/platinum doublet works just as well as the standard anthracycline-containing regimen.

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    News

    Differences in right vs. left colon in Black vs. White individuals

    Author:
    M. Alexander Otto, PA, MMS
    Publish date: January 14, 2021

    Differences between right and left colon biopsy specimens may explain the difference in colorectal cancer...

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    News

    Differences in right vs. left colon in Black vs. White individuals

    Author:
    M. Alexander Otto, PA, MMS
    Publish date: January 8, 2021

    Differences between right and left colon biopsy specimens may explain the difference in colorectal cancer...

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    News

    Prospects dim for Medicare drug reimbursement cuts

    Author:
    M. Alexander Otto, PA, MMS
    Publish date: December 17, 2020

    A proposal to lower Medicare Part B reimbursements for 50 physician-administered drugs and biologics to what drug manufacturers receive for them...

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    News

    Patients with lung and blood cancers most vulnerable to COVID-19

    Author:
    M. Alexander Otto, PA, MMS
    Publish date: December 10, 2020

    Patients with leukemia, non-Hodgkin lymphoma, and lung cancer are at greatest risk.

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