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Sex-discordant transfusions don’t increase death risk
Photo by Elise Amendola There is no association between sex-discordant blood transfusions and the risk of death after cardiac surgery, according...
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EC grants drug orphan designation for PNH
The European Commission (EC) has granted orphan drug designation to RA101495 for the treatment of paroxysmal nocturnal hemoglobinuria (PNH)....
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CAR T-cell trial placed on hold again
Once again, the phase 2 ROCKET trial has been placed on clinical hold due to patient deaths. In this trial, researchers are testing the chimeric...
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EC grants drug orphan status for AML, sarcoma
The European Commission (EC) has granted orphan drug designation to crenolanib for the treatment of acute myeloid leukemia (AML) and soft tissue...
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Study supports palliative care in HSCT recipients
Photo by Chad McNeeley Palliative care can be beneficial for patients undergoing hematopoietic stem cell transplant (HSCT) to treat hematologic...
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EC approves nivolumab for relapsed/refractory cHL
Photo from Business Wire The European Commission (EC) has approved nivolumab (Opdivo) for the treatment of adults with relapsed or refractory...
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Statins increase bleeding risk with dabigatran
Photo courtesy of St.
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EC expands indication for arsenic trioxide in APL
Image courtesy of the Armed Forces Institute of Pathology The European Commission (EC) has extended the approved indication for arsenic trioxide...
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Drug approved to treat hemophilia A in Kuwait
(Elocta) packaging Photo courtesy of Sobi The Ministry of Health in Kuwait has approved efmoroctocog alfa (Elocta®), a recombinant human factor...
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Novel CLL drugs could greatly increase costs
New research suggests the increasing use of oral targeted therapies for chronic lymphocytic leukemia (CLL) could raise US treatment costs for the...
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ALL subtype ‘highly prevalent’ in adults
Photo courtesy of St.
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FDA approves new uses for drug in MM
Photo courtesy of Janssen The US Food and Drug Administration (FDA) has approved new indications for the monoclonal antibody daratumumab (...
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NCCN guidelines on MM now include MRD testing
The National Comprehensive Cancer Network (NCCN) has revised its clinical practice guidelines on multiple myeloma (MM) to include response...
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Large-scale tumor profiling deemed feasible, but challenges remain
Photo courtesy of the National Institute of General Medical Sciences New research suggests large-scale genomic profiling is technically feasible...
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Improving cryopreservation of RBCs
Photo from UAB Hospital A class of small-molecule ice recrystallization inhibitors could improve the cryopreservation of red blood cells (RBCs)...