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Team explains how artemisinin kills malaria parasite
infecting a red blood cell Photo courtesy of St.
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Education may increase clinical trial participation
Photo courtesy of NCI and Matthews Media Group A new study suggests that educating cancer patients about clinical trials—with either a general or...
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Study reveals germline variants in AML, other cancers
A study published in Nature Communications has shed light on the hereditary elements of 12 cancer types. Investigators looked for rare germline...
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Drug disappoints in phase 3 HSCT trial
Brincidofovir did not prevent clinically significant cytomegalovirus (CMV) infection through week 24 after hematopoietic stem cell transplant (...
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De novo mutation linked to FA subtype
with Fanconi anemia Researchers say they have established the cause of a subtype of Fanconi anemia (FA)—a de novo mutation in 1 allele of RAD51,...
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Women can take anticoagulants and hormones safely, study suggests
A study published in Blood indicates that women on anticoagulants can take estrogen-containing contraception or hormone replacement therapy...
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Combo prolongs PFS in phase 3 MM trial
Photo by Bill Branson Results of the phase 3 ENDEAVOR trial suggest combination carfilzomib and dexamethasone prolongs progression-free survival...
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LAAC a better long-term value than anticoagulants, team says
Photo courtesy of Boston Scientific Researchers have compared the cost-effectiveness of left atrial appendage closure (LAAC) with the Watchman...
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Antihemophilic factor meets phase 3 endpoint
An antihemophilic factor that was recently approved in the US has met the primary endpoint of a phase 3 study, according to the product’s maker,...
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Protein discovery could have therapeutic implications
Photo courtesy of The Scripps Research Institute New research shows how NPM1—a protein implicated in non-Hodgkin lymphoma, acute myelogenous...
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Anemia tied to cognitive impairment
A population-based study conducted in Germany has suggested a link between anemia and mild cognitive impairment (MCI). Researchers found that...
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Antibody shows promise for treating CLL
Preclinical research suggests a humanized monoclonal antibody called cirmtuzumab (UC-961) might be an effective treatment for chronic lymphocytic...
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FDA changes deferral policy for MSM blood donors
Photo by Михаило Јовановић The US Food and Drug Administration (FDA) has issued a final guidance outlining updated blood donor deferral...
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Survey reveals need to evaluate EOL discussions
Photo courtesy of the National Cancer Institute and Mathews Media Group End-of-life (EOL) discussions often occur “too late” for patients with...
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CHMP recommends FVIII product for hemophilia A
The European Medicines Agency’s Committee for Medicinal Products for Human Use (CHMP) has recommended BAY 81-8973, a recombinant factor VIII (...