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FDA approves biosimilar filgrastim
The US Food and Drug Administration (FDA) has approved the leukocyte growth factor Nivestym™ (filgrastim-aafi), a biosimilar to Neupogen (...
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Tool may reveal optimal time for SCT in MF
A new tool can help patients with myelofibrosis (MF) decide when to pursue stem cell transplant (SCT), according to the MPN Research Foundation....
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Diabetics have higher risk of hematologic, other cancers
A review of data from more than 19 million people indicates that diabetes significantly raises a person’s risk of developing cancer. When...
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L-glutamine reduces complications of SCD
Results of a phase 3 trial showed that L-glutamine can reduce complications of sickle cell disease (SCD). SCD patients who received...
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How ALL invades the CNS
Researchers believe they have solved the mystery of how acute lymphoblastic leukemia (ALL) infiltrates the central nervous system (CNS)....
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Study suggests dasatinib could treat AML, JMML
New research suggests dasatinib could treat certain patients with juvenile myelomonocytic leukemia (JMML) or acute myeloid leukemia (AML). The...
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FDA grants UCB product orphan designation
The US Food and Drug Administration (FDA) has granted orphan drug designation to NiCord for hematopoietic stem cell transplant. NiCord is created...
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Product receives orphan designation for use in HSCT
The US Food and Drug Administration (FDA) has granted orphan drug designation to dilanubicel (NLA101) for the reduction of morbidity and mortality...
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Explaining enasidenib resistance in AML
New research helps explain enasidenib resistance among patients with IDH2-mutant acute myeloid leukemia (AML). Researchers found that leukemic...
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Investigators question utility of SFLCA
Researchers are questioning the clinical usefulness of the serum free light chain assay (SFLCA) for patients with monoclonal gammopathies. The...
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Vaccine protects mice from malaria
An RNA replicon-based vaccine can fight malaria infection in mice, according to research published in Nature Communications. The vaccine targets...
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Turbulence aids platelet production
Turbulence promotes large-scale production of functional platelets from human induced pluripotent stem cells (hiPSCs), according to research...
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Study links gut bacteria and TRALI
A new study has revealed a previously unknown link between gastrointestinal flora and transfusion-related acute lung injury (TRALI). “We observed...
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Protein could be target for MLL-rearranged AML
Preclinical research has revealed a potential therapeutic target for MLL-rearranged acute myeloid leukemia (AML). The target—F-box protein S-...
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FDA releases guidance docs on gene therapy
The US Food and Drug Administration (FDA) has released several draft guidance documents on gene therapy. Three are disease-specific guidances—for...