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Gut microbiota and symptoms of psychosis: Is there a link?
Gut microbiome changes in schizophrenia may be symptom-specific.
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Depression and schizophrenia: Many biological and clinical similarities
Clinicians generally regard major depressive disorder (MDD) and schizophrenia as 2 separate and distinct psychiatric brain disorders.
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Contemporary psychiatry: A SWOT analysis
A look at our medical specialty’s strengths, weaknesses, opportunities, and threats.
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From debate to stalemate and hate: An epidemic of intellectual constipation
Groupthink is hazardous, especially when perfused with religious fervor.
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Optimal psychiatric treatment: Target the brain and avoid the body
Pharmacotherapy for psychiatric disorders is a mixed blessing.
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More on social entropy
As leaders of the American Psychiatric Association, we received dozens of communications from members who were shocked by the discriminatory and...
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Is evolution’s greatest triumph its worst blunder?
Of all the dazzling achievements of evolution, the most glorious by far is the emergence of the advanced human brain, especially the prefrontal...
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Lamotrigine for bipolar depression?
In reading Dr. Nasrallah's August 2022 editorial (“Reversing depression: A plethora of therapeutic strategies and mechanisms,” Current Psychiatry...
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The accelerating societal entropy undermines mental health
According to the second law of thermodynamics, it is inevitable that entropy will continue to increase over time.
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Faulty fences: Blood-brain barrier dysfunction in schizophrenia
The blood-brain barrier (BBB) is an essential barrier of closely spaced cells that regulates entry into the CNS.
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From neuroplasticity to psychoplasticity: Psilocybin may reverse personality disorders and political fanaticism
One of psychiatry’s long-standing dogmas is that personality disorders are enduring, unchangeable, and not amenable to treatment with potent...
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Reversing depression: A plethora of therapeutic strategies and mechanisms
Despite much progress, major depressive disorder (MDD) continues to be a challenging and life-threatening neuropsychiatric disorder. It is highly...
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3 steps to bend the curve of schizophrenia
Schizophrenia is arguably the most serious psychiatric brain syndrome. It disables teens and young adults and robs them of their potential and...
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A PSYCHIATRIC MANIFESTO: Stigma is hate speech and a hate crime
Having witnessed the devastating impact of stigma on patients with mental illness throughout my psychiatric career, I am fed up and disgusted with...
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The neurobiology of Jeopardy! champions
As a regular viewer of Jeopardy! I find it both interesting and educational. But the psychiatric neuroscientist in me marvels at...