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Families with pulmonary fibrosis share trends in disease evolution
Age at diagnosis may have potential as a screening tool for unaffected relatives of familial pulmonary fibrosis patients.
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Consistent primary care beforehand may reduce mortality after emergency surgery
The protective effect of primary care was similar for Black and White patients up to 180 days.
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Verbal working memory deterioration predicts relapse in remitted psychosis
Declines in verbal working memory were observed 2 months before a relapse in multiple models.
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Phenotypes drive antibiotic response in youth with bronchiectasis
Ethnicity and auscultatory findings were factors predicting response; data may improve antibiotic stewardship.
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LAMA-LABA surpasses corticosteroid combination as COPD therapy
Large matched cohort study suggests stronger safety and effectiveness outcomes with LAMA-LABA inhalers vs. ICS-LABA inhalers.
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Spirometry predicts mortality in type 2 diabetes
PRISm occurs in approximately 10% of the general population and has been identified as a predictor of adverse health outcomes.
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Colorectal cancer: Younger patients fare worse
Genetic data also showed increased prevalence of certain mutations in early-onset patients.
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Vaginal microbiota transfer may affect neurodevelopment in cesarean infants
The value of vaginal microbiota to improve infant outcomes remains uncertain, but safety data are strong.
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Comorbid respiratory disease key predictor of NTM-PD
Overall, comorbid respiratory disease was significantly associated with an increased risk of NTM-PD.
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Consider mental health and social factors in management of sickle cell disease
Screen sickle cell disease patients for depression and mental health issues, especially those reporting higher levels of pain.
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Depression drives metabolic syndrome
The association between baseline depression and development of metabolic syndrome was strongest for those with severe depression.
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Electronic nose may sniff out early lung cancer in COPD
Molecular profiling of exhaled breath using electronic nose (eNose) technology has shown potential as a method of early detection by identifying...
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Molecular mechanisms may predict major depressive disorder
Six miRNAs distinguished depressed patients from healthy controls with reasonable accuracy and could act as biomarkers in research and treatment...
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Cell activity in psoriasis may predict disease severity and provide clues to comorbidities
Skin samples from patients with psoriasis showed more fibroblast clusters in the upper layers of the skin in moderate to severe cases.
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Ovarian cancer: Sequencing strategy identifies biomarker that could guide treatment
Novel sequencing strategy appears to be a reliable predictor of homologous recombination DNA repair deficiency.