News
Post-MI beta-blockers: Less is more
Major finding: Patients discharged post MI on a beta-blocker at roughly 25% of the target dose – which was established as conferring a survival...
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ACC/AHA cardiovascular risk equations get a thumbs-up
Major finding: The controversial cardiovascular risk equations at the heart of the latest ACC/AHA risk-assessment guidelines turned in a moderate...
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ACC/AHA Cardiovascular Risk Equations Get a Thumbs-up
Major finding: The controversial cardiovascular risk equations at the heart of the latest ACC/AHA risk-assessment guidelines turned in a moderate...
News
Crushing ticagrelor tablets sped platelet inhibition
Major finding: Mean plasma concentration of ticagralor was roughly fivefold greater 30 minutes post dose via a crushed tablet in water vs.
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Ultrasound-facilitated endovascular thrombolysis 'a game changer' in acute pulmonary embolism
Major finding: Ultrasound-facilitated, catheter-directed, low-dose fibrinolysis in patients with high-risk pulmonary embolism improved right...
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Off-label use of novel anticoagulants accelerates
Major finding: By the fourth quarter of 2012, 14.9% of patients with nonvalvular AF were on a novel anticoagulant. So were 13.8% of those with...
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'Favorable signal' for secondary coronary prevention in STABILITY
Major finding: The combined rate of cardiovascular death, myocardial infarction, or stroke in patients randomized to darapladib was 9.7%, yielding...
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Antipsychotics’ risk in dementia revised upward
Major finding: Among elderly patients with dementia placed on an antipsychotic to treat behavioral problems, the number needed to harm – that is,...
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Asenapine often beneficial in geriatric bipolar disorder
Major finding: The atypical antipsychotic asenapine produced significant improvement in symptoms and mood in patients with later-life bipolar...
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Apixaban provides larger medical cost savings than other NOACs
Major finding: Using apixaban instead of warfarin for stroke prevention in AF would result in an estimated medical cost savings of $1,245 per...
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Surprising new findings about late-life schizophrenia
Major finding: Quality of life in older persons with schizophrenia changed significantly either for better or for worse over the course of 52...
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ECT electrode placement matters most in elderly
Major finding: Right unilateral ECT provided a 70.4% remission rate in severely depressed patients aged 60 or older, compared with a 46% rate in...
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Evolocumab betters ezetimibe for lowering LDL in statin-intolerant patients
Major finding: Statin-intolerant patients with hypercholesterolemia experienced mean 53%-56% reductions in LDL cholesterol in response to 12 weeks...