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Rising viral load on dolutegravir? Investigators try fix before switch
“If you can get through those difficult phases, people can go back on their meds,” he said in an interview. “It’s almost a sociological problem...
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Results from halted islatravir antiretroviral trial presented
Because of persistent concerns about the impact on CD4+ T cells and total lymphocytes, another phase 3 trial is now underway using a lower 0.25 mg...
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Injecting long-acting antiretrovirals into clinic care
In the peer staff program, workers are trained in a 4-month medical residency–style program that shows them how to test for HIV, inject long-...
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UNAIDS targets: Progress reported, but ‘HIV is far from over’
New infections persist at a rate that has not dropped as fast as possible.
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Daily statin cuts cardiovascular risk in HIV
“These are types of people who, if they came to the doctor’s office right now before REPRIEVE, they would largely be told your risk score is not...
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Patient selection key to lowering placebo response rates in lupus clinical trials
High placebo response rates in lupus clinical trials are making it difficult to show treatment effectiveness.
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Strategies for complete B-cell depletion evolve for patients with lupus nephritis
Growing evidence suggests more complete B-cell depletion in patients with lupus nephritis is associated with a greater likelihood of treatment...
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Investigational lupus drug cenerimod moves to phase 3 studies after equivocal phase 2 results
Novel S1P1 receptor modulator cenerimod shows impact on disease activity in lupus, with more pronounced benefits in those with more severe disease...
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Early remission in lupus nephritis can still progress to advanced CKD
Patients with lupus nephritis who achieve complete remission within 1 year of starting treatment can still progress to advanced chronic kidney...
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Biomarkers for measuring lupus nephritis treatment response gain ground
A panel of protein biomarkers in urine could achieve better identification of lupus nephritis patients who are likely to respond to treatment.
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Running does not cause lasting cartilage damage
A single bout of running causes only transient and small changes to the thickness and structure of healthy cartilage in the knee.
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Ustekinumab matches TNF inhibitors for psoriatic arthritis in 3-year, real-world study
A real-world study comparing the interleukin-12/23 inhibitor ustekinumab with tumor necrosis factor inhibitors for psoriatic arthritis found...
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Hydroxychloroquine risk found in some older patients with RA
Hydroxychloroquine initiation in older patients with rheumatoid arthritis and a history of heart failure was associated with an increased risk of...
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Gout app improves treat to target, reduces flares
A smartphone app to help patients communicate their urate levels to clinicians means more achieve treatment targets and experience fewer flares....
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No excess mortality seen in contemporary undifferentiated arthritis
Patients who meet the contemporary criteria for undifferentiated arthritis do not appear to have an increase in excess mortality, unlike those who...