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Guselkumab Efficacy in Crohn’s Disease Unaffected by Prior Biologic Use
Almost all patients in the biologic-inadequate response group had previously received at least one anti–tumor necrosis factor agent, and around 15...
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Patients With IBD More Likely to Develop, or Have Prior, T1D
Patients with IBD had a moderately increased risk for T1D and higher odds of having prior T1D than the general population.
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Ultraprocessed Foods Associated With Relapse Risk in Crohn’s Disease
This is the first prospective study of this particular level of UPFs in people with Crohn’s disease who are in remission.
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Cendakimab That Targets IL-13 Shows Promise in Eosinophilic Esophagitis
Treatment with cendakimab also improved key endoscopic and histologic features, even in patients who had an inadequate response or intolerance to...
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When It Comes to Polyp Diagnosis With CADx, Location Matters
“The key questions here relate to why are these systems underperforming in the proximal colon, and how can we improve this?” said Dr. David Graham...
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Exocrine Pancreatic Insufficiency: Optimal PERT Dose Varies by Primary Pancreatic Disease
Successful PERT is defined as the resolution of nutritional deficiencies and relief of symptoms and signs associated with insufficiency.
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Type 2 Diabetes: Insulin-Free for 24 Months After Novel Endoscopic Procedure
At the 24-month follow-up, 11 patients were still insulin-free while maintaining A1c levels below 7.5%.
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GPs Urged to Embed Lifestyle Medicine into Primary Care
“If the doctors are moving, they’re much more likely to promote it, and if they’re eating well, they’re much more likely to be able to be...
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New Guidelines Emphasize Liver Care in T2D, Obesity
The guideline recognizes that individuals with type 2 diabetes or obesity with additional metabolic risk factor(s) are at a higher risk for MASLD...
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‘Remarkable’ Weight Loss Seen With Safe, Tolerable Novel Oral Combination
A dual-pathway, oral weight loss drug resulted in up to 13% body weight loss, finds Phase 1 study.
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Early vs Late Fast Window: Is One More Effective?
The study found that 8 hours of time-restriced eating — whether early or late in the day — led to a significant improvement in the time spent...
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Significant Benefit with Liver Transplantation in ACLF: CHANCE Study
The findings highlight “the inadequacy of current transplant allocation criteria for patients with ACLF 2 and 3,” said Dr. Rajiv Jalan.
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‘Dramatic’ Phase 2 Results for Survodutide in MASH, Fibrosis
Fifty percent of patients on 2.4- and 6-mg doses experienced a statistically significant improvement in fibrosis without worsening of MASH.
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Seladelpar Shows Clinically Meaningful Improvements in PBC
The 2-year analysis also showed that seladelpar, a first-in-class, orally active agent, was safe and well tolerated.
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Tirzepatide Shows Improvements in MASH Resolution, Fibrosis
Tirzepatide also led to weight loss in patients.