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Mortality post perioperative CPR climbs with patient frailty
The current analysis provides “a heretofore absent base of evidence to guide decision-making regarding CPR in patients with frailty who undergo...
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Aspirin not the best antiplatelet for CAD secondary prevention in meta-analysis
“Taken together, our data challenge the central role of aspirin in secondary prevention and support a paradigm shift toward P2Y12 inhibitor...
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Expanded coverage of carotid stenting in CMS draft proposal
The decision proposal would expand coverage for CAS “to standard surgical risk patients by removing the limitation of coverage to only high...
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Peripartum cardiomyopathy raises risks at future pregnancy despite LV recovery
The study suggests that “women with PPCM need long-term follow-up by cardiology, as mortality does not abate over time.”
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New definition for iron deficiency in CV disease proposed
A broader implication is that “we should revise how we define iron deficiency in heart failure and cardiovascular disease in general, and how we...
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Lean muscle mass protective against Alzheimer’s?
The finding suggesting that lean mass is associated with better cognitive function is “important, as cognitive impairment can become stable rather...
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Do oral contraceptives increase depression risk?
The authors also didn’t study the indication for OC use. Several medical conditions are treated with OCs, including premenstrual dysphoric...
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Can a repurposed Parkinson’s drug slow ALS progression?
One expert interviewed for this article said the study “falls short of being a credible 1/2a clinical trial.”
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Concomitant med use may explain poor antidepressant response
“Many widely prescribed medications ... are associated with depression side effects,” said Dr. Mark Olfson.
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B vitamin may help boost antidepressant efficacy
“This is a ‘shortcut’ that gets directly to the brain,” said Dr. Vladimir Maletic.
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Ketamine may be a viable alternative to ECT for severe depression
This was an “extraordinarily important and clinically relevant study, large, well-designed, and well-conducted,” said Dr. Dan Iosifescu.
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Internet use a modifiable dementia risk factor in older adults?
“Online engagement can develop and maintain cognitive reserve – resiliency against physiological damage to the brain – and increased cognitive...
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Disrupted gut microbiome a key driver of major depression?
Investigators found that MDD had specific metabolic “signatures” consisting of 124 metabolites that spanned energy and lipid pathways, with some...
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Walnuts linked to improved attention, psychological maturity in teens
Clinicians should advise adolescents “to eat a handful of walnuts three times a week for the rest of their lives. They may have a healthier brain...
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Predicting BPD vs. bipolar treatment response: New imaging data
“This study can help clinicians with clinical prediction of treatment efficacy between BD and BPD and clarify the neural mechanism of treatment,”...